Transmission Raman Spectroscopy (TRS)

Demonstration of Transmission Raman Spectroscopy (TRS)

Transmission Raman Spectroscopy is a method for analysing diffusely scattering materials such as powders, tablets, suspensions and other chemical mixtures. It is ideally suited to rapid quantitative analysis of pharmaceutical dosage forms and mixtures, which is the main purpose of Cobalt’s TRS100 instrument. The benefits include:

  • Bulk quantification of intact formulations – the whole of the tablet is measured without sub-sampling
  • Suppresses interfering surface fluorescence and Raman signals from capsules and coatings
  • Penetrates >10mm into powders and tablets
  • Rapid analysis times (seconds or less per sample)
  • Accuracy to ca. 1% relative error
  • No sample preparation

More information is available in our Technical and Application Notes Section.

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